Renal Impairment Contraindication
A hospitalized 90-year-old woman was prescribed her chronic diuretic medication, hydrochlorothiazide. During her hospitalization, she suffered from severe renal impairment, which negatively affects the drug’s safety. MedAware identified and alerted on the changes, and the treatment was replaced.
If given while suffering from severe renal impairment, the patient’s renal dysfunction could have been aggravated to the point of renal failure and the patient would have failed to realize the intended diuretic and antihypertensive effects of the medication.